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Dosimetric Comparison of Non-Small-Cell Lung Cancer with Helical Tomotherapy Plans and Intensity-Modulated Radiation Therapy Plans


Z Liang

Zhan Liang*, Zijian Zhang , Rongrong Zhou , Xiangya Hospital Central South University, Changsha, Hunan

Presentations

SU-I-GPD-T-369 (Sunday, July 30, 2017) 3:00 PM - 6:00 PM Room: Exhibit Hall


Purpose: The aim of this study was to compare helical tomotherapy (HT)and intensity-modulated radiation therapy (IMRT) plans for non-small-cell lung cancer (NSCLC) and evaluate the irradiated dose of planning target volume(PTV) and organs at risk(OARs).

Methods: Nine cases of NSCLC patients were investigated by developing a HT plan and an IMRT plan,both plans were made by auto planning system and evaluated by means of the dose coverage of the target and dose-volume histograms(DVH).The prescription dose were 60Gy/30F for the PTV.The dose restriction for OARs were as follows:V20 to total lung≤35%,V30 to heart≤40%,V40 to heart ≤30%,the maximum dose to spinal cord was 45Gy.

Results: The dose radiation volume (V5,V10,V20) to total lung and mean lung dose(MLD) in the HT plan were lower than those in the IMRT plan(P<0.05),but the dose radiation volume (V10,V20,V30,V40) to heart increased in the HT plan(P<0.05).The maximum dose of spinal cord and mean heart dose(MHD) have no difference in the two plans.

Conclusion: The HT plan provide a better dose radiation volume to lung and MLD,but it can increase the dose radiation to heart.


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