Program Information
To Measure Dose Volume Variations Amongst the Pelvis IMRT Plans
c li*, J Lu , Y Yin , Shandong Cancer Hospital Affiliated to Shandong;Shandong Cancer Hospital and Institute, Jinan, Shandong Province
Presentations
SU-I-GPD-T-410 (Sunday, July 30, 2017) 3:00 PM - 6:00 PM Room: Exhibit Hall
Purpose: To study the dose volume histogram difference of target and organs at risk in IMRT planning of cervical cancer.
Methods: 30 patients with cervical cancer were retrospectively analyzed. Five groups of DVH curves for PTV and the endocrine organs (bladder, rectum and left and right femoral heads) were derived from the Pinnacle3 planning system. The mean DVH curves and interquartile range (IQR) of volume as a function of dose were calculated for each group of DVH curves.
Results: The maximum volume variation for PTV is reached at IQRvol (54.03Gy) = 6.95%. The maximum volume variation for bladder was reached at IQRvol (17.24Gy) = 14.62%.V40 and V30 for bladder were 32.79 ± 7.06% and 56.47 ± 9.94%, respectively. Rectal DVH showed the largest difference at 35.92 Gy, with the quartile of 19.94%. V40 and V30 for rectum were 30.17 ± 10.80% and 58.16 ± 11.99%, respectively. Differences in IQRvol reached significance for bladder and rectum(p<0.05). The maximum volume variation for left femoral head was reached at IQRvol (16.06Gy)= 31.47%. The maximum volume variation for right femoral head was reached at IQRvol (17.47Gy)= 32.82%.
Conclusion: Quartile range curve of DVHs can be used to analyze the deviations of DVH curve of target and organs at risk, and provide guidance for automatic planning optimization parameter setting.
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