Program Information
The Stability of Radiomics Features On 4D FDG-PET/CT Images
C Ma1*, (1) Shandong Cancer Hospital and Institute, Jinan, Shandong
Presentations
SU-F-R-21 (Sunday, July 31, 2016) 3:00 PM - 6:00 PM Room: Exhibit Hall
Purpose:
The aim of our study was to perform a stability analysis of 4D PET-derived features in non-small cell lung carcinoma (NSCLC) based on six different respiratory phases.
Methods:
The 4D FDG-PET/CT respiratory phases were labeled as T0%, T17%, T33%,T50%, T67%, T83% phases, with the T0% phase approximately corresponding to the normal end-inspiration. Lesions were manually delineated based on fused PET-CT, using a standardized clinical delineation protocol. Six texture parameters were analyzed.
Results:
Results showed that the majority of assessed features had a low stability such as Homogeneity (0.385₋0.416), Dissimilarity (3.707₋3.861),Angular two moments (0.013₋0.019), Contrast (39.782₋49.562), Entropy(4.683₋5.002) and Inverse differential moment (0.317₋0.362) on different respiratory phases.
Conclusion:
This study suggest that further research of quantitative PET imaging features is warranted with respect to respiratory motion.
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