Program Information
Internal Dosimetry in Nuclear Medicine Using GATE and XCAT Phantom: A Simulation Study
M Fallahpoor1*, M Abbasi1 , A Sen2 , A Parach3 , F Kalantari4 , (1) Tehran University of Medical Sciences, Vali-Asr Hospital, Tehran, Tehran, (2) University of Houston, Houston, Texas, (3) Shahid Sadoughi University of Medical Sciences, Yazd, Yazd, (4) UT Southwestern Medical Center, Dallas, Texas
Presentations
SU-E-T-507 (Sunday, July 12, 2015) 3:00 PM - 6:00 PM Room: Exhibit Hall
Purpose:Monte Carlo simulations are routinely used for internal dosimetry studies. These studies are conducted with humanoid phantoms such as the XCAT phantom. In this abstract we present the absorbed doses for various pairs of source and target organs using three common radiotracers in nuclear medicine.
Methods: The GATE software package is used for the Monte Carlo simulations. A typical female XCAT phantom is used as the input. Three radiotracers 153Sm, 131I and 99mTc are studied. The Specific Absorbed Fraction (SAF) for gamma rays (99mTc, 153Sm and 131I) and Specific Fraction (SF) for beta particles (153Sm and 131I) are calculated for all 100 pairs of source target organs including brain, liver, lung, pancreas, kidney, adrenal, spleen, rib bone, bladder and ovaries.
Results: The source organs themselves gain the highest absorbed dose as compared to other organs. The dose is found to be inversely proportional to distance from the source organ. In SAF results of 153Sm, when the source organ is lung, the rib bone, gain 0.0730 (Kg-1) that is more than lung itself.
Conclusion: The absorbed dose for various organs was studied in terms of SAF and SF. Such studies hold importance for future therapeutic procedures and optimization of induced radiotracer.
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