Program Information
Novel Quality Assurance Procedure for the Small Animal Radiation Research Platform Using Commercial OSLDs
J Keller1*, V Lockamy1 , S Glenn2 , A Harrison1 , (1) Thomas Jefferson University, Philadelphia, PA, (2) Xstrahl Inc., Suwanee, GA
Presentations
SU-E-T-575 (Sunday, July 12, 2015) 3:00 PM - 6:00 PM Room: Exhibit Hall
Purpose: To support radiobiological research with the Xstrahl small animal radiation research platform (SARRP) by developing a simple and effective method using commercially available optically stimulated luminescent dosimeters (OSLDs) that ensures dose output consistency.
Methods: The SARRP output is calibrated according to the vendor standards and TG-61 protocol utilizing an ADCL calibrated ion chamber and electrometer at 2 cm depth of solid water. A cross calibration is performed by replacing the ion chamber with five OSLDs at the 2 cm depth. The OSLDs are irradiated to 500 cGy with 220 keV at 13 mA (78s delivery time) with a copper filter for an uncollimated 17x17 cm² aperture. Instead of the absolute dose, the total amount of raw counts are collected from the OSLD reader and used for analysis. This constancy procedure was performed two more times over the course of three weeks with two OLSDs for validity.
Results: The average reading for all OSLDs is 494939 with a 1-sigma standard deviation of the 5.8%. With an acceptable dose output range of ±10%, the OSLD readings have a counts range of [445445, 544433].
Conclusion: This method of using nanoDot™ OSLDs to perform output constancy checks for the SARRP ensures the output of the device is within 10% from the time of calibration and is convenient as well as time efficient. Because this, the frequency of output checks can be increased, which can improve the output stability for research with this device. The output trend of the SARRP will continue to be monitored in the future to establish a timeline for constancy checks and recalibration.
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