Program Information
Radiation Exposure Comparisons of CESM with 2D FFDM and 3D Tomosynthesis Mammography
J James*, T Boltz , W Pavlicek , Mayo Clinic Arizona, Scottsdale, AZ
Presentations
TU-CD-207-4 (Tuesday, July 14, 2015) 10:15 AM - 12:15 PM Room: 207
Purpose:While mammography is considered the standard for front-line breast cancer screening, image sensitivity and specificity can be affected by factors like dense breast tissue. Contrast-enhanced spectral mammography (CESM) shows promising initial results for dense breasts but comes at the cost of increased dose compared with full-field-digital-mammography (FFDM). The goal of this study is to quantitatively assess the dose increase of CESM in comparison with 2D-FFDM and 3D-Tomo at varying breast thickness.
Methods:The experiments were conducted on a Hologic-Selenia-Dimensions system that performed 2D-FFDM, 3D-Tomo and CESM (high and low energies) on regular (50/50) and dense (70/30) breast tissue-mimicking phantoms. Both the phantoms had 6, 1-cm thick slabs (total thickness 6cm), compressed at 20-lbs using an 18x24 paddle. A single exposure was performed for each of the 3 mammo techniques with the following settings: AEC-Auto; Focal Spot-Large; kVp-Auto; mAs-Auto, Target/Filter combination-Auto; AEC Sensor/Exposure compensation Step-2/0. Average glandular dose (AGD) in mGy was obtained and compared as a function of breast thickness (1 – 6 cm) for both the phantom types.
Results:The study shows that dose from the total CESM from 50/50 phantom at a breast thickness of a) 4.5 cm was 37.5% higher than 2D-FFDM and 30% higher than 3D-Tomo, b) 6 cm was 36.2% higher than 2D-FFDM and 41% higher than 3D-Tomo. For a dense breast tissue of 70/30 phantom, it was found that CESM dose at a breast thickness of: a) 4.5 cm was 33.3% higher than 2D-FFDM and 28.8% higher than 3D-Tomo, b) 6 cm was 35.4% higher than 2D-FFDM and 48.0% higher than 3D-Tomo. The overall CESM dose for the dense breast phantom was 12.5% higher at 4.5cm and 35% higher at 6 cm compared to the 50/50 phantom.
Conclusion:This quantitative comparison study showed that CESM technique has an increased radiation dose compared to conventional 2D-FFDM and 3D-Tomo.
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