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Feasibility Study On MRI-Based BANG3 Gel Dosimetry Using Dual-Source Parallel RF Transmission System
S Kim1*, H Baek2 , J Lee1 , D Lee1 , S Lee1 , B Choe1 , (1) The Catholic University of Korea, Seoul, Seoul, (2) Korea Basic Science Institute, Chungwon, Chungwon
Presentations
SU-E-J-71 Sunday 3:00PM - 6:00PM Room: Exhibit HallPurpose: In this work, we present the feasibility of use of the parallel RF transmission with multiple RF source (MultiTransmit) imaging in MRI-based polymer gel dosimetry.
Methods: The commercially available BANG3 gel was used for gel dosimetry. Spin-spin relaxation rate R2 was used to quantify the absorbed dose. The image quality (signal-to-noise ratio, SNR; image uniformity) and B1 field inhomogeneity between conventional single-source and MultiTransmit MR imaging were compared. Finally, the estimated R2 uncertainty σ(R2) and dosimetric performance (i.e., dose resolution) between conventional single-source and MultiTransmit MR imaging were compared.
Results: Image quality and B1 field homogeneity within each calibration vial and large phantom was statistically better in MultiTransmit imaging than in conventional single-source RF transmission imaging (P < 0.005 for all calibration vials). In particular, σ(R2) (defined as the standard uncertainty of R2) was lower on the MultiTransmit images than on the conventional single-source images. Furthermore, the MultiTransmit measurement gives a lower than that obtained using the conventional single-source method.
Conclusion: The improved image quality and B1 homogeneity resulted in reduced dose uncertainty (i.e., σ(R2) and dose resolution) in MRI-based polymer gel dosimetry, suggesting that MultiTransmit MR imaging has potential benefits for use in clinical 3D gel dosimetry without the need for the complicated B1 field correction method.
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