Program Information

Dosimetric Dependence On the Collimator Angle in Prostate Volumetric Modulated Arc Therapy

m khan

m khan¹*, j rehman² , M Khan³ , J Chow⁴ , (1) ,,,(2) the islaimia university of bahawalpur,, Bahawalpur, punjab, (3) the islaimia university of bahawalpur,, Bahawalpur, punjab, (4) Princess Margaret Cancer Center, Toronto, ON

Presentations

SU-E-T-604 Sunday 3:00PM - 6:00PM Room: Exhibit Hall

Purpose:
The purpose of this study is to investigate the dose-volume variations of planning target volume (PTV) and organs-at-risk (OARs) in prostate volumetric modulated arc therapy (VMAT) when using different collimator angles. It is because collimator angle awareness is essential for planner to produce an optimal prostate VMAT plan in a rational time.

Methods:
Single-arc VMAT plans at different collimator angles (0o, 15o, 30o, 45o, 60o, 75o and 90o) were created systematically using a Harold heterogeneous pelvis phantom. For each change of collimator angle, a new plan was re-optimized for that angle. The prescription dose was 78 Gy per 39 fractions. Conformity index (CI), homogeneity index (HI), gradient index, machine monitor unit, dose-volume histogram, the mean and maximum doses of the PTV were calculated and analyzed. On the other hand, dose-volume histogram, the mean and maximum doses of the OARs such as bladder, rectum and femoral heads for different collimator angles were determined from the plans.

Results:
There was no significance difference, based on the plan dose-volume evaluation criteria, found in the VMAT optimizations for all studied collimator angles. Higher CI and lower HI were found for the 45o collimator angle. In addition, the 15o collimator angle provided lower HI similar to the 45o collimator angle. The 75o and 90o collimator angle were found good for the rectum sparing, and the 75o and 30o collimator angle were found good for the right and left femur sparing, respectively. The PTV dose coverage for each plan was comparatively independent of the collimator angle.

Conclusion:
The dosimetric results in this study are useful to the planner to select different collimator angles to improve the PTV coverage and OAR sparing in prostate VMAT.


Contact Email: