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Total Body Irradiation with a Compensator Fabricated Using a 3D Optical Scanner and a 3D Printer

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S Park

S Park*1,2,3,4, C Choi1,2,3,4 , M Chun1,2,3,5 , J Kim1,2,3 , J Han1,3 , J Cho1,3 , Y Kim1,3 , J Park1,2,3,4 (1) Department of Radiation Oncology, Seoul National University Hospital, Seoul, 03080, Republic of Korea,(2) Institute of Radiation Medicine, Seoul National University Medical Research Center, Seoul, 03080, Republic of Korea,(3) Biomedical Research Institute, Seoul National University Hospital, Seoul, 03080, Republic of Korea, (4) Center for Convergence Research on Robotics, Advanced Institutes of Convergence Technology, Suwon, 16229, Republic of Korea, (5) Interdisciplinary Program in Radiation Applied Life Science, Seoul National University College of Medicine, Seoul, 03080, Republic of Korea

Presentations

TU-L-GePD-TT-5 (Tuesday, August 1, 2017) 1:15 PM - 1:45 PM Room: Therapy ePoster Theater


Purpose: We propose modified bilateral total body irradiation (TBI) with compensators manufactured with a 3D printer and a 3D optical scanner.

Methods: We acquired surface information of an anthropomorphic phantom with the 3D optical scanner and fabricated the 3D compensator with the 3D printer, which could continuously compensate for the lateral missing tissue of an entire body from the beam’s eye view. To test the system’s performance, we measured doses with optically stimulated luminescent dosimeters (OSLDs) as well as EBT3 films with the anthropomorphic phantom during TBI without a compensator (no comp. TBI), conventional bilateral TBI (conv. TBI), and TBI with the 3D compensator (3D TBI).

Results: The 3D TBI showed the most uniform dose delivery to the phantom. From the OSLD measurements of the 3D TBI, the deviations between the measured doses and the prescription dose ranged from −6.7% to 2.4% (from -7.8% to 32.2% for no comp. TBI and from -8.8% to 5.3% for conv. TBI) inside the phantom and from −2.3% to 0.6% (from 2.9% to 33.4% for no comp. TBI and from 0.4% to 6.1% for conv. TBI) on the phantom’s surface. From the EBT3 film measurements, the prescription dose could be delivered to the entire body of the phantom within ±10% accuracy, except for the chest region, where tissue heterogeneity is severe. The 3D TBI doses were much more uniform than those of the other irradiation techniques, especially in the anterior-to-posterior direction.

Conclusion: 3D TBI could deliver a more uniform dose to an entire body than did conventional bilateral TBI. 3D TBI could reflect the continuous body surface changes with the 3D scanned information. In summary, the 3D TBI was advantageous, owing to its uniform dose delivery as well as its efficient treatment procedure.


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