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Clinical Implementation of Intraoperative Electron Radiation Therapy (IOeRT)

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M Hussain

T Amin , A Azzam , R Mahmood , Z Eltahir , H Selham , B Moftah , M Hussain*, King Faisal Specialist Hospital & Research Center, Riyadh, Riyadh

PO-BPC-Exhibit Hall-24 Saturday  Room: Exhibit Hall

Purpose: Intra-Operative electron Radiation therapy (IOeRT) is one of the developed technologies uses mobile linear accelerators for post-resection patient treatment offers flexibility inside the operating room (OR). The overall implementation process of IOeRT is discussed here.

Methods: The IOeRT delivering mobile linac equipped with electron energies 6, 9 and 12 MeV is warmed up with 500 MUs for each beam in the morning of the patient treatment. The dose output, energy ratio and some of the safety tests are performed by a radiation physicist. The IOeRT candidate patients are resected in OR followed by a possible single fraction electron dose to the tumor-bed to treat residual disease.

Results: Out of 11 patients treated to-date, 30 to 75 year old, 10 male and 1 female, almost 75% will be receiving post-surgical chemotherapy. Along with Pancreatic, retroperitoneal para-aortic, urinary bladder treatment sites, almost half of the sites were portahepatis lymph nodes (LNs) and celiac LNs. A separate work is in process of compilation of pathological data.

The single fraction doses ranging 10 Gy to 20 Gy were delivered using cones of mixed bevel angles 0, 15 and 30 degree, diameter ranging 6 cm to 10 cm with 0.5 cm bolus used in almost every treatment.

The radiation therapy was delivered successfully as per clinical protocols including AAPM TG-72 guidelines. The pathological data analysis is in compilation stage for further analysis. The clinical outcomes would be presented separately after clinical follow up data is available in coming months.

Conclusion: The IOeRT with high energy and high dose rate electron beams is a viable modality for pelvis and abdominal regions.


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